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Protective Effects of the mTOR Inhibitor Everolimus on Cytoskeletal Injury in Human Podocytes Are Mediated by RhoA Signaling

Podocytes are highly differentiated kidney cells playing an important role in maintaining the glomerular filtration barrier. Particularly, the integrity of the actin cytoskeleton is crucial as cytoskeletal damage associated with foot process effacement and loss of slit diaphragms constitutes a major...

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Detalles Bibliográficos
Autores principales:	Jeruschke, Stefanie, Büscher, Anja Katrin, Oh, Jun, Saleem, Moin Ahson, Hoyer, Peter Friedrich, Weber, Stefanie, Nalbant, Perihan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572151/ https://www.ncbi.nlm.nih.gov/pubmed/23418489 http://dx.doi.org/10.1371/journal.pone.0055980

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