Photodynamic Therapy (PDT): PDT Mechanisms

Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in oncology a photosensitizing agent is applied and then activated by a specific wavelength and energy of light. This light energy in the presence of oxygen will lead to the creation of the photodynamic reaction...

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Detalles Bibliográficos
Autores principales: Allison, Ron R., Moghissi, Keyvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Gastrointestinal Endoscopy 2013
Materias:
Focused Review Series: Photodynamic Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572346/
https://www.ncbi.nlm.nih.gov/pubmed/23422955
http://dx.doi.org/10.5946/ce.2013.46.1.24
Descripción
Sumario:Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in oncology a photosensitizing agent is applied and then activated by a specific wavelength and energy of light. This light energy in the presence of oxygen will lead to the creation of the photodynamic reaction which is cyto and vasculo toxic. This paper will review the mechanisms of action of PDT and how they may be manipulated to improve clinical outcome in cancer patients.

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