Population pharmacokinetics of phenytoin after intravenous administration of fosphenytoin sodium in pediatric patients, adult patients, and healthy volunteers

PURPOSE: We performed a population pharmacokinetic analysis of phenytoin after intravenous administration of fosphenytoin sodium in healthy, neurosurgical, and epileptic subjects, including pediatric patients, and determined the optimal dose and infusion rate for achieving the therapeutic range. MET...

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Detalles Bibliográficos
Autores principales: Tanaka, Jun, Kasai, Hidefumi, Shimizu, Kenji, Shimasaki, Shigeki, Kumagai, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572369/
https://www.ncbi.nlm.nih.gov/pubmed/22918614
http://dx.doi.org/10.1007/s00228-012-1373-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572369/
https://www.ncbi.nlm.nih.gov/pubmed/22918614
http://dx.doi.org/10.1007/s00228-012-1373-8

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