MRI for attenuation correction in PET: methods and challenges

In current combined PET/MR systems, PET attenuation correction is based on MRI, since the small bore inside MRI systems and the strong magnetic field do not permit a rotating PET transmission source or a CT device to be integrated. Unlike CT measurements in PET/CT scanners, the MR signal is not dire...

Descripción completa

Detalles Bibliográficos
Autores principales: Wagenknecht, Gudrun, Kaiser, Hans-Jürgen, Mottaghy, Felix M., Herzog, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572388/
https://www.ncbi.nlm.nih.gov/pubmed/23179594
http://dx.doi.org/10.1007/s10334-012-0353-4
_version_ 1782259314947260416
author Wagenknecht, Gudrun
Kaiser, Hans-Jürgen
Mottaghy, Felix M.
Herzog, Hans
author_facet Wagenknecht, Gudrun
Kaiser, Hans-Jürgen
Mottaghy, Felix M.
Herzog, Hans
author_sort Wagenknecht, Gudrun
collection PubMed
description In current combined PET/MR systems, PET attenuation correction is based on MRI, since the small bore inside MRI systems and the strong magnetic field do not permit a rotating PET transmission source or a CT device to be integrated. Unlike CT measurements in PET/CT scanners, the MR signal is not directly correlated to tissue density and thus cannot be converted by a simple transformation of intensity values. Various approaches have been developed based on templates, atlas information, direct segmentation of T1-weighted MR images, or segmentation of images from special MR sequences. The advantages and disadvantages of these approaches as well as additional challenges will be discussed in this review.
format Online
Article
Text
id pubmed-3572388
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-35723882013-02-21 MRI for attenuation correction in PET: methods and challenges Wagenknecht, Gudrun Kaiser, Hans-Jürgen Mottaghy, Felix M. Herzog, Hans MAGMA Review Article In current combined PET/MR systems, PET attenuation correction is based on MRI, since the small bore inside MRI systems and the strong magnetic field do not permit a rotating PET transmission source or a CT device to be integrated. Unlike CT measurements in PET/CT scanners, the MR signal is not directly correlated to tissue density and thus cannot be converted by a simple transformation of intensity values. Various approaches have been developed based on templates, atlas information, direct segmentation of T1-weighted MR images, or segmentation of images from special MR sequences. The advantages and disadvantages of these approaches as well as additional challenges will be discussed in this review. Springer-Verlag 2012-11-21 2013 /pmc/articles/PMC3572388/ /pubmed/23179594 http://dx.doi.org/10.1007/s10334-012-0353-4 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Review Article
Wagenknecht, Gudrun
Kaiser, Hans-Jürgen
Mottaghy, Felix M.
Herzog, Hans
MRI for attenuation correction in PET: methods and challenges
title MRI for attenuation correction in PET: methods and challenges
title_full MRI for attenuation correction in PET: methods and challenges
title_fullStr MRI for attenuation correction in PET: methods and challenges
title_full_unstemmed MRI for attenuation correction in PET: methods and challenges
title_short MRI for attenuation correction in PET: methods and challenges
title_sort mri for attenuation correction in pet: methods and challenges
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572388/
https://www.ncbi.nlm.nih.gov/pubmed/23179594
http://dx.doi.org/10.1007/s10334-012-0353-4
work_keys_str_mv AT wagenknechtgudrun mriforattenuationcorrectioninpetmethodsandchallenges
AT kaiserhansjurgen mriforattenuationcorrectioninpetmethodsandchallenges
AT mottaghyfelixm mriforattenuationcorrectioninpetmethodsandchallenges
AT herzoghans mriforattenuationcorrectioninpetmethodsandchallenges

Ejemplares similares