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Gremlin induces cell proliferation and extra cellular matrix accumulation in mouse mesangial cells exposed to high glucose via the ERK1/2 pathway

BACKGROUND: Gremlin, a bone morphogenetic protein antagonist, plays an important role in the pathogenesis of diabetic nephropathy (DN). However, the specific molecular mechanism underlying Gremlin’s involvement in DN has not been fully elucidated. In the present study, we investigated the role of Gr...

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Detalles Bibliográficos
Autores principales:	Huang, Haixia, Huang, Haiying, Li, Ying, Liu, Maodong, Shi, Yonghong, Chi, Yanqing, Zhang, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572428/ https://www.ncbi.nlm.nih.gov/pubmed/23394397 http://dx.doi.org/10.1186/1471-2369-14-33

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