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Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa

Aberrant methylation of CpG islands (CGI) occurs in many genes expressed in colonic epithelial cells, and may contribute to the dysregulation of signalling pathways associated with carcinogenesis. This cross-sectional study assessed the relative importance of age, nutritional exposures and other env...

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Detalles Bibliográficos
Autores principales:	Tapp, Henri S, Commane, Daniel M, Bradburn, D Michael, Arasaradnam, Ramesh, Mathers, John C, Johnson, Ian T, Belshaw, Nigel J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572581/ https://www.ncbi.nlm.nih.gov/pubmed/23157586 http://dx.doi.org/10.1111/acel.12030

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