Cargando…
Crystal structures of murine angiogenin-2 and -3 – probing ‘structure – function’ relationships amongst angiogenin homologues
Angiogenin (Ang) is a potent inducer of neovascularization. Point mutations in human Ang have been linked to cancer progression and two neurodegenerative diseases: amyotrophic lateral sclerosis and Parkinson's disease. Intensive structural and functional analyses of Ang have been paramount in a...
Autores principales: | Iyer, Shalini, Holloway, Daniel E, Acharya, K Ravi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Inc
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572582/ https://www.ncbi.nlm.nih.gov/pubmed/23170778 http://dx.doi.org/10.1111/febs.12071 |
Ejemplares similares
-
Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule()
por: Thiyagarajan, Nethaji, et al.
Publicado: (2012) -
Mutational dynamics of murine angiogenin duplicates
por: Codoñer, Francisco M, et al.
Publicado: (2010) -
Structural and functional implications of positive selection at the primate angiogenin gene
por: Osorio, Daniel S, et al.
Publicado: (2007) -
Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons
por: Thiyagarajan, Nethaji, et al.
Publicado: (2012) -
Structure of angiogenin dimer bound to double-stranded RNA
por: Sievers, Katharina, et al.
Publicado: (2022)