RORC2 Gene Silencing in Human Th17 Cells by siRNA: Design and Evaluation of Highly Efficient siRNA

BACKGROUND: RNA interference-based gene silencing has recently been applied as an efficient tool for functional gene analysis. RORC2 is the key transcription factor orchestrating Th17 cells differentiation, the cells that are known as the pathogenic elements in various autoimmune diseases. The aim o...

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Detalles Bibliográficos
Autores principales: Hakemi, Mazdak Ganjalikhani, Ghaedi, Kamran, Andalib, Alireza, Homayouni, Vida, Hosseini, Mohsen, Rezaei, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572701/
https://www.ncbi.nlm.nih.gov/pubmed/23626872

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