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Analysis of the Functional Polymorphism in the Cytochrome P450 CYP2C8 Gene rs11572080 with Regard to Colorectal Cancer Risk

In addition to the known effects on drug metabolism and response, functional polymorphisms of genes coding for xenobiotic-metabolizing enzymes (XME) play a role in cancer. Genes coding for XME act as low-penetrance genes and confer modest but consistent and significant risks for a variety of cancers...

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Detalles Bibliográficos
Autores principales:	Ladero, José M., Agúndez, José A. G., Martínez, Carmen, Amo, Gemma, Ayuso, Pedro, García-Martín, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572883/ https://www.ncbi.nlm.nih.gov/pubmed/23420707 http://dx.doi.org/10.3389/fgene.2012.00278

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