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Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells
Loss of the Merlin tumour suppressor causes abnormal de-differentiation and proliferation of Schwann cells and formation of schwannoma tumours in patients with neurofibromatosis type 2. Within the mature peripheral nerve the normal development, differentiation and maintenance of myelinating and non-...
Autores principales: | Doddrell, Robin D. S., Dun, Xin-Peng, Shivane, Aditya, Feltri, M. Laura, Wrabetz, Lawrence, Wegner, Michael, Sock, Elisabeth, Hanemann, C. Oliver, Parkinson, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572932/ https://www.ncbi.nlm.nih.gov/pubmed/23413263 http://dx.doi.org/10.1093/brain/aws353 |
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