Regulation of the Membrane Insertion and Conductance Activity of the Metamorphic Chloride Intracellular Channel Protein CLIC1 by Cholesterol

The Chloride Intracellular ion channel protein CLIC1 has the ability to spontaneously insert into lipid membranes from a soluble, globular state. The precise mechanism of how this occurs and what regulates this insertion is still largely unknown, although factors such as pH and redox environment are...

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Detalles Bibliográficos
Autores principales: Valenzuela, Stella M., Alkhamici, Heba, Brown, Louise J., Almond, Oscar C., Goodchild, Sophia C., Carne, Sonia, Curmi, Paul M. G., Holt, Stephen A., Cornell, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572944/
https://www.ncbi.nlm.nih.gov/pubmed/23457643
http://dx.doi.org/10.1371/journal.pone.0056948

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