Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

Asthma is a common chronic respiratory disease characterized by airway hyperresponsiveness (AHR). The genetics of asthma have been widely studied in mouse and human, and homologous genomic regions have been associated with mouse AHR and human asthma-related phenotypes. Our goal was to identify asthm...

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Detalles Bibliográficos
Autores principales: Himes, Blanca E., Sheppard, Keith, Berndt, Annerose, Leme, Adriana S., Myers, Rachel A., Gignoux, Christopher R., Levin, Albert M., Gauderman, W. James, Yang, James J., Mathias, Rasika A., Romieu, Isabelle, Torgerson, Dara G., Roth, Lindsey A., Huntsman, Scott, Eng, Celeste, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley J., Lemanske, Robert F., Zeiger, Robert S., Strunk, Robert C., Martinez, Fernando D., Boushey, Homer, Chinchilli, Vernon M., Israel, Elliot, Mauger, David, Koppelman, Gerard H., Postma, Dirkje S., Nieuwenhuis, Maartje A. E., Vonk, Judith M., Lima, John J., Irvin, Charles G., Peters, Stephen P., Kubo, Michiaki, Tamari, Mayumi, Nakamura, Yusuke, Litonjua, Augusto A., Tantisira, Kelan G., Raby, Benjamin A., Bleecker, Eugene R., Meyers, Deborah A., London, Stephanie J., Barnes, Kathleen C., Gilliland, Frank D., Williams, L. Keoki, Burchard, Esteban G., Nicolae, Dan L., Ober, Carole, DeMeo, Dawn L., Silverman, Edwin K., Paigen, Beverly, Churchill, Gary, Shapiro, Steve D., Weiss, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572953/
https://www.ncbi.nlm.nih.gov/pubmed/23457522
http://dx.doi.org/10.1371/journal.pone.0056179

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