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Enhanced T Cell Lymphoma in NOD.Stat5b Transgenic Mice Is Caused by Hyperactivation of Stat5b in CD8(+) Thymocytes

Activation of signal transducers and activators of transcription (STAT) proteins may be critical to their oncogenic functions as demonstrated by the development of B-cell lymphoma/leukemia in transgenic (TG) mice overexpressing a constitutively activated form of Stat5b. However, low incidence of CD8...

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Detalles Bibliográficos
Autores principales: Chen, Bo, Yi, Bing, Mao, Rui, Liu, Haitao, Wang, Jinhua, Sharma, Ashok, Peiper, Stephen, Leonard, Warren J., She, Jin-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572980/
https://www.ncbi.nlm.nih.gov/pubmed/23457589
http://dx.doi.org/10.1371/journal.pone.0056600