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Headbobber: A Combined Morphogenetic and Cochleosaccular Mouse Model to Study 10qter Deletions in Human Deafness

The recessive mouse mutant headbobber (hb) displays the characteristic behavioural traits associated with vestibular defects including headbobbing, circling and deafness. This mutation was caused by the insertion of a transgene into distal chromosome 7 affecting expression of native genes. We show t...

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Detalles Bibliográficos
Autores principales: Buniello, Annalisa, Hardisty-Hughes, Rachel E., Pass, Johanna C., Bober, Eva, Smith, Richard J., Steel, Karen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572983/
https://www.ncbi.nlm.nih.gov/pubmed/23457544
http://dx.doi.org/10.1371/journal.pone.0056274