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Bioactivity-Guided Identification and Cell Signaling Technology to Delineate the Lactate Dehydrogenase A Inhibition Effects of Spatholobus suberectus on Breast Cancer
Aerobic glycolysis is an important feature of cancer cells. In recent years, lactate dehydrogenase A (LDH-A) is emerging as a novel therapeutic target for cancer treatment. Seeking LDH-A inhibitors from natural resources has been paid much attention for drug discovery. Spatholobus suberectus (SS) is...
Autores principales: | Wang, Zhiyu, Wang, Dongmei, Han, Shouwei, Wang, Neng, Mo, Feizhi, Loo, Tjing Yung, Shen, Jiangang, Huang, Hui, Chen, Jianping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572989/ https://www.ncbi.nlm.nih.gov/pubmed/23457597 http://dx.doi.org/10.1371/journal.pone.0056631 |
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