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Interplay of Protein and DNA Structure Revealed in Simulations of the lac Operon
The E. coli Lac repressor is the classic textbook example of a protein that attaches to widely spaced sites along a genome and forces the intervening DNA into a loop. The short loops implicated in the regulation of the lac operon suggest the involvement of factors other than DNA and repressor in gen...
Autores principales: | Czapla, Luke, Grosner, Michael A., Swigon, David, Olson, Wilma K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572996/ https://www.ncbi.nlm.nih.gov/pubmed/23457581 http://dx.doi.org/10.1371/journal.pone.0056548 |
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