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rs12976445 variant in the pri-miR-125a correlates with a lower level of hsa-miR-125a and ERBB2 overexpression in breast cancer patients

Expression of MIR125A is diminished in breast tumors, however the reason for the hsa-mir-125a decrease in the cancer is not known. HER2 is encoded by ERBB2, a target for hsa-miR-125a which interacts with the 3′UTR of ERBB2 mRNA. The present study reveals that a polymorphism (rs12976445) within the p...

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Detalles Bibliográficos
Autores principales:	LEHMANN, TOMASZ P., KORSKI, KONSTANTY, IBBS, MATHEW, ZAWIERUCHA, PIOTR, GRODECKA-GAZDECKA, SYLWIA, JAGODZIŃSKI, PAWEŁ P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573016/ https://www.ncbi.nlm.nih.gov/pubmed/23420759 http://dx.doi.org/10.3892/ol.2012.1040

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