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Suppression of XBP1S Mediates High Glucose-Induced Oxidative Stress and Extracellular Matrix Synthesis in Renal Mesangial Cell and Kidney of Diabetic Rats

Recent evidences suggest that endoplasmic reticulum (ER) stress was involved in multi pathological conditions, including diabetic nephropathy (DN). X-box binding protein 1(XBP1), as a key mediator of ER stress, has been proved having the capability of preventing oxidative stress. In this study, we i...

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Detalles Bibliográficos
Autores principales: Shao, Decui, Liu, Jia, Ni, Jun, Wang, Zhen, Shen, Yang, Zhou, Li, Huang, Yu, Wang, Jun, Xue, Hong, Zhang, Wei, Lu, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573021/
https://www.ncbi.nlm.nih.gov/pubmed/23457509
http://dx.doi.org/10.1371/journal.pone.0056124