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Krüppel-Like Factor 2 Is Required for Normal Mouse Cardiac Development

Krüppel-like factor 2 (KLF2) is expressed in endothelial cells in the developing heart, particularly in areas of high shear stress, such as the atrioventricular (AV) canal. KLF2 ablation leads to myocardial thinning, high output cardiac failure and death by mouse embryonic day 14.5 (E14.5) in a mixe...

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Detalles Bibliográficos
Autores principales:	Chiplunkar, Aditi R., Lung, Tina K., Alhashem, Yousef, Koppenhaver, Benjamin A., Salloum, Fadi N., Kukreja, Rakesh C., Haar, Jack L., Lloyd, Joyce A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573061/ https://www.ncbi.nlm.nih.gov/pubmed/23457456 http://dx.doi.org/10.1371/journal.pone.0054891

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