Tysnd1 Deficiency in Mice Interferes with the Peroxisomal Localization of PTS2 Enzymes, Causing Lipid Metabolic Abnormalities and Male Infertility

Peroxisomes are subcellular organelles involved in lipid metabolic processes, including those of very-long-chain fatty acids and branched-chain fatty acids, among others. Peroxisome matrix proteins are synthesized in the cytoplasm. Targeting signals (PTS or peroxisomal targeting signal) at the C-ter...

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Detalles Bibliográficos
Autores principales: Mizuno, Yumi, Ninomiya, Yuichi, Nakachi, Yutaka, Iseki, Mioko, Iwasa, Hiroyasu, Akita, Masumi, Tsukui, Tohru, Shimozawa, Nobuyuki, Ito, Chizuru, Toshimori, Kiyotaka, Nishimukai, Megumi, Hara, Hiroshi, Maeba, Ryouta, Okazaki, Tomoki, Alodaib, Ali Nasser Ali, Amoudi, Mohammed Al, Jacob, Minnie, Alkuraya, Fowzan S., Horai, Yasushi, Watanabe, Mitsuhiro, Motegi, Hiromi, Wakana, Shigeharu, Noda, Tetsuo, Kurochkin, Igor V., Mizuno, Yosuke, Schönbach, Christian, Okazaki, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573110/
https://www.ncbi.nlm.nih.gov/pubmed/23459139
http://dx.doi.org/10.1371/journal.pgen.1003286

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