Therapeutic Efficacy of Antibodies Lacking FcγR against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies

Dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) are life-threatening complications following infection with one of the four serotypes of dengue virus (DENV). At present, no vaccine or antiviral therapies are available against dengue. Here, we characterized a panel of eight human or mous...

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Detalles Bibliográficos
Autores principales: Williams, Katherine L., Sukupolvi-Petty, Soila, Beltramello, Martina, Johnson, Syd, Sallusto, Federica, Lanzavecchia, Antonio, Diamond, Michael S., Harris, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573116/
https://www.ncbi.nlm.nih.gov/pubmed/23459315
http://dx.doi.org/10.1371/journal.ppat.1003157

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