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Biodamage via shock waves initiated by irradiation with ions

Radiation damage following the ionising radiation of tissue has different scenarios and mechanisms depending on the projectiles or radiation modality. We investigate the radiation damage effects due to shock waves produced by ions. We analyse the strength of the shock wave capable of directly produc...

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Detalles Bibliográficos
Autores principales: Surdutovich, Eugene, Yakubovich, Alexander V., Solov'yov, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573355/
https://www.ncbi.nlm.nih.gov/pubmed/23411473
http://dx.doi.org/10.1038/srep01289
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author Surdutovich, Eugene
Yakubovich, Alexander V.
Solov'yov, Andrey V.
author_facet Surdutovich, Eugene
Yakubovich, Alexander V.
Solov'yov, Andrey V.
author_sort Surdutovich, Eugene
collection PubMed
description Radiation damage following the ionising radiation of tissue has different scenarios and mechanisms depending on the projectiles or radiation modality. We investigate the radiation damage effects due to shock waves produced by ions. We analyse the strength of the shock wave capable of directly producing DNA strand breaks and, depending on the ion's linear energy transfer, estimate the radius from the ion's path, within which DNA damage by the shock wave mechanism is dominant. At much smaller values of linear energy transfer, the shock waves turn out to be instrumental in propagating reactive species formed close to the ion's path to large distances, successfully competing with diffusion.
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spelling pubmed-35733552013-02-15 Biodamage via shock waves initiated by irradiation with ions Surdutovich, Eugene Yakubovich, Alexander V. Solov'yov, Andrey V. Sci Rep Article Radiation damage following the ionising radiation of tissue has different scenarios and mechanisms depending on the projectiles or radiation modality. We investigate the radiation damage effects due to shock waves produced by ions. We analyse the strength of the shock wave capable of directly producing DNA strand breaks and, depending on the ion's linear energy transfer, estimate the radius from the ion's path, within which DNA damage by the shock wave mechanism is dominant. At much smaller values of linear energy transfer, the shock waves turn out to be instrumental in propagating reactive species formed close to the ion's path to large distances, successfully competing with diffusion. Nature Publishing Group 2013-02-15 /pmc/articles/PMC3573355/ /pubmed/23411473 http://dx.doi.org/10.1038/srep01289 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Article
Surdutovich, Eugene
Yakubovich, Alexander V.
Solov'yov, Andrey V.
Biodamage via shock waves initiated by irradiation with ions
title Biodamage via shock waves initiated by irradiation with ions
title_full Biodamage via shock waves initiated by irradiation with ions
title_fullStr Biodamage via shock waves initiated by irradiation with ions
title_full_unstemmed Biodamage via shock waves initiated by irradiation with ions
title_short Biodamage via shock waves initiated by irradiation with ions
title_sort biodamage via shock waves initiated by irradiation with ions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573355/
https://www.ncbi.nlm.nih.gov/pubmed/23411473
http://dx.doi.org/10.1038/srep01289
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