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Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts

To evaluate the stain removal efficacy of a novel dentifrice containing papain and bromelain extracts (Glodent) in comparison with a control dentifrice (Colgate regular). This was a randomized, positive-controlled, double-blinded, clinical study. Subjects were randomly divided into one of the two st...

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Autores principales: Chakravarthy, PK, Acharya, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573376/
https://www.ncbi.nlm.nih.gov/pubmed/23493413
http://dx.doi.org/10.4103/0975-1483.104368
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author Chakravarthy, PK
Acharya, S
author_facet Chakravarthy, PK
Acharya, S
author_sort Chakravarthy, PK
collection PubMed
description To evaluate the stain removal efficacy of a novel dentifrice containing papain and bromelain extracts (Glodent) in comparison with a control dentifrice (Colgate regular). This was a randomized, positive-controlled, double-blinded, clinical study. Subjects were randomly divided into one of the two study groups. Pre-treatment and post treatment photographs of the 4 anterior teeth were recorded under standardized conditions and analyzed for lightness or luminosity values using Adobe Photoshop. The difference between the mean pre-treatment luminosity of test and control groups was not statistically significant. In both test and control groups, the post-treatment luminosity was significantly higher than pre- treatment luminosity (P < 0.001 and P = 0.003 respectively). The mean post-treatment luminosity for test group was found to be significantly higher than control group. The mean percentage removal of stains for test group was significantly higher than control group. The test dentifrice showed significant stain removal when compared to control which could be attributed to the role of proteolytic enzymes in the test dentifrice.
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spelling pubmed-35733762013-03-14 Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts Chakravarthy, PK Acharya, S J Young Pharm Pharmacology To evaluate the stain removal efficacy of a novel dentifrice containing papain and bromelain extracts (Glodent) in comparison with a control dentifrice (Colgate regular). This was a randomized, positive-controlled, double-blinded, clinical study. Subjects were randomly divided into one of the two study groups. Pre-treatment and post treatment photographs of the 4 anterior teeth were recorded under standardized conditions and analyzed for lightness or luminosity values using Adobe Photoshop. The difference between the mean pre-treatment luminosity of test and control groups was not statistically significant. In both test and control groups, the post-treatment luminosity was significantly higher than pre- treatment luminosity (P < 0.001 and P = 0.003 respectively). The mean post-treatment luminosity for test group was found to be significantly higher than control group. The mean percentage removal of stains for test group was significantly higher than control group. The test dentifrice showed significant stain removal when compared to control which could be attributed to the role of proteolytic enzymes in the test dentifrice. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3573376/ /pubmed/23493413 http://dx.doi.org/10.4103/0975-1483.104368 Text en Copyright: © Journal of Young Pharmacists http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Pharmacology
Chakravarthy, PK
Acharya, S
Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts
title Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts
title_full Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts
title_fullStr Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts
title_full_unstemmed Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts
title_short Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts
title_sort efficacy of extrinsic stain removal by novel dentifrice containing papain and bromelain extracts
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573376/
https://www.ncbi.nlm.nih.gov/pubmed/23493413
http://dx.doi.org/10.4103/0975-1483.104368
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