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Clinical variants, stages, and management of basal cell carcinoma
Basal cell carcinoma (BCC) is the most common paraneoplastic disease among human neoplasms. The tumor affects mainly photoexposed areas, most often in the head and seldom appears on genitalia and perigenital region. BCC progresses slowly and metastases are found in less than 0.5% of the cases; howev...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573444/ https://www.ncbi.nlm.nih.gov/pubmed/23439912 http://dx.doi.org/10.4103/2229-5178.105456 |
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author | Dourmishev, Lyubomir A. Rusinova, Darena Botev, Ivan |
author_facet | Dourmishev, Lyubomir A. Rusinova, Darena Botev, Ivan |
author_sort | Dourmishev, Lyubomir A. |
collection | PubMed |
description | Basal cell carcinoma (BCC) is the most common paraneoplastic disease among human neoplasms. The tumor affects mainly photoexposed areas, most often in the head and seldom appears on genitalia and perigenital region. BCC progresses slowly and metastases are found in less than 0.5% of the cases; however, a considerable local destruction and mutilation could be observed when treatment is neglected or inadequate. Different variants as nodular, cystic, micronodular, superficial, pigment BCC are described in literature and the differential diagnosis in some cases could be difficult. The staging of BCC is made according to Tumor, Node, Metastasis (TNM) classification and is essential for performing the adequate treatment. Numerous therapeutic methods established for treatment of BCC, having their advantages or disadvantages, do not absolutely dissolve the risk of relapses. The early diagnostics based on the good knowledge and timely organized and adequate treatment is a precondition for better prognosis. Despite the slow progress and numerous therapeutic methods, the basal cell carcinoma should not be underestimated. |
format | Online Article Text |
id | pubmed-3573444 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-35734442013-02-22 Clinical variants, stages, and management of basal cell carcinoma Dourmishev, Lyubomir A. Rusinova, Darena Botev, Ivan Indian Dermatol Online J Review Article Basal cell carcinoma (BCC) is the most common paraneoplastic disease among human neoplasms. The tumor affects mainly photoexposed areas, most often in the head and seldom appears on genitalia and perigenital region. BCC progresses slowly and metastases are found in less than 0.5% of the cases; however, a considerable local destruction and mutilation could be observed when treatment is neglected or inadequate. Different variants as nodular, cystic, micronodular, superficial, pigment BCC are described in literature and the differential diagnosis in some cases could be difficult. The staging of BCC is made according to Tumor, Node, Metastasis (TNM) classification and is essential for performing the adequate treatment. Numerous therapeutic methods established for treatment of BCC, having their advantages or disadvantages, do not absolutely dissolve the risk of relapses. The early diagnostics based on the good knowledge and timely organized and adequate treatment is a precondition for better prognosis. Despite the slow progress and numerous therapeutic methods, the basal cell carcinoma should not be underestimated. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3573444/ /pubmed/23439912 http://dx.doi.org/10.4103/2229-5178.105456 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Dourmishev, Lyubomir A. Rusinova, Darena Botev, Ivan Clinical variants, stages, and management of basal cell carcinoma |
title | Clinical variants, stages, and management of basal cell carcinoma |
title_full | Clinical variants, stages, and management of basal cell carcinoma |
title_fullStr | Clinical variants, stages, and management of basal cell carcinoma |
title_full_unstemmed | Clinical variants, stages, and management of basal cell carcinoma |
title_short | Clinical variants, stages, and management of basal cell carcinoma |
title_sort | clinical variants, stages, and management of basal cell carcinoma |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573444/ https://www.ncbi.nlm.nih.gov/pubmed/23439912 http://dx.doi.org/10.4103/2229-5178.105456 |
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