A Rare Case of Inherited Factor-II Deficiency Causing Life-Threatening Menorrhagia

Menorrhagia is a common gynecological symptom. In adolescents, the cause is generally dysfunctional uterine bleeding. Menorrhagia may also be due to undiagnosed coagulation defects, endocrine disorders, gynecological abnormalities of the uterus, or other systemic disorders. Menorrhagia may be the only clinical manifestation of an inherited bleeding disorder. We report a case of inherited hypoprothrombinemia (factor II deficiency), a rare bleeding disorder as the cause of life-threatening menorrhagia. In the absence of a readily identifiable cause, all adolescents with menorrhagia should be examined for bleeding disorders.