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Kdo Hydrolase Is Required for Francisella tularensis Virulence and Evasion of TLR2-Mediated Innate Immunity

The highly virulent Francisella tularensis subsp. tularensis has been classified as a category A bioterrorism agent. A live vaccine strain (LVS) has been developed but remains unlicensed in the United States because of an incomplete understanding of its attenuation. Lipopolysaccharide (LPS) modifica...

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Detalles Bibliográficos
Autores principales:	Okan, Nihal A., Chalabaev, Sabina, Kim, Tae-Hyun, Fink, Avner, Ross, Robin A., Kasper, Dennis L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573668/ https://www.ncbi.nlm.nih.gov/pubmed/23404403 http://dx.doi.org/10.1128/mBio.00638-12

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