Burkitt's Lymphoma Presenting as Late-Onset Posttransplant Lymphoproliferative Disorder following Kidney and Pancreas Transplantation: Case Report and Review of the Literature

Posttransplant lymphoproliferative disorders (PTLD) are a rare, but serious complication following transplantation. Late-onset PTLD are often associated with more monoclonal lesions and consequently have a worse prognosis. There are only isolated case reports of Burkitt's lymphoma presenting as...

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Autores principales: Naik, Seema, Tayapongsak, Kristy, Robbins, Katherine, Manavi, Cyrus Koresh, Pettenati, Mark J., Grier, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Published online: January, 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573821/
https://www.ncbi.nlm.nih.gov/pubmed/23466659
http://dx.doi.org/10.1159/000346346
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author Naik, Seema
Tayapongsak, Kristy
Robbins, Katherine
Manavi, Cyrus Koresh
Pettenati, Mark J.
Grier, David D.
author_facet Naik, Seema
Tayapongsak, Kristy
Robbins, Katherine
Manavi, Cyrus Koresh
Pettenati, Mark J.
Grier, David D.
author_sort Naik, Seema
collection PubMed
description Posttransplant lymphoproliferative disorders (PTLD) are a rare, but serious complication following transplantation. Late-onset PTLD are often associated with more monoclonal lesions and consequently have a worse prognosis. There are only isolated case reports of Burkitt's lymphoma presenting as PTLD. We present an extremely rare, aggressive Burkitt's lymphoma years after kidney and pancreas transplantation which was successfully treated with combination chemotherapy along with withdrawal of immunosuppression. The patient remains in complete remission more than 2 years after his diagnosis. We also provide a succinct review of treatment of various PTLD and discuss the role of Epstein-Barr virus infection in the pathogenesis of PTLD.
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spelling pubmed-35738212013-03-05 Burkitt's Lymphoma Presenting as Late-Onset Posttransplant Lymphoproliferative Disorder following Kidney and Pancreas Transplantation: Case Report and Review of the Literature Naik, Seema Tayapongsak, Kristy Robbins, Katherine Manavi, Cyrus Koresh Pettenati, Mark J. Grier, David D. Case Rep Oncol Published online: January, 2013 Posttransplant lymphoproliferative disorders (PTLD) are a rare, but serious complication following transplantation. Late-onset PTLD are often associated with more monoclonal lesions and consequently have a worse prognosis. There are only isolated case reports of Burkitt's lymphoma presenting as PTLD. We present an extremely rare, aggressive Burkitt's lymphoma years after kidney and pancreas transplantation which was successfully treated with combination chemotherapy along with withdrawal of immunosuppression. The patient remains in complete remission more than 2 years after his diagnosis. We also provide a succinct review of treatment of various PTLD and discuss the role of Epstein-Barr virus infection in the pathogenesis of PTLD. S. Karger AG 2013-01-08 /pmc/articles/PMC3573821/ /pubmed/23466659 http://dx.doi.org/10.1159/000346346 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: January, 2013
Naik, Seema
Tayapongsak, Kristy
Robbins, Katherine
Manavi, Cyrus Koresh
Pettenati, Mark J.
Grier, David D.
Burkitt's Lymphoma Presenting as Late-Onset Posttransplant Lymphoproliferative Disorder following Kidney and Pancreas Transplantation: Case Report and Review of the Literature
title Burkitt's Lymphoma Presenting as Late-Onset Posttransplant Lymphoproliferative Disorder following Kidney and Pancreas Transplantation: Case Report and Review of the Literature
title_full Burkitt's Lymphoma Presenting as Late-Onset Posttransplant Lymphoproliferative Disorder following Kidney and Pancreas Transplantation: Case Report and Review of the Literature
title_fullStr Burkitt's Lymphoma Presenting as Late-Onset Posttransplant Lymphoproliferative Disorder following Kidney and Pancreas Transplantation: Case Report and Review of the Literature
title_full_unstemmed Burkitt's Lymphoma Presenting as Late-Onset Posttransplant Lymphoproliferative Disorder following Kidney and Pancreas Transplantation: Case Report and Review of the Literature
title_short Burkitt's Lymphoma Presenting as Late-Onset Posttransplant Lymphoproliferative Disorder following Kidney and Pancreas Transplantation: Case Report and Review of the Literature
title_sort burkitt's lymphoma presenting as late-onset posttransplant lymphoproliferative disorder following kidney and pancreas transplantation: case report and review of the literature
topic Published online: January, 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573821/
https://www.ncbi.nlm.nih.gov/pubmed/23466659
http://dx.doi.org/10.1159/000346346
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