The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection

The ubiquitous distribution of vitamin D receptors in the human body is responsible for the pleiotropic effects of vitamin D-receptor activation. We discuss the possible beneficial effects of a selective activator of vitamin D receptor, paricalcitol, on the cardiovascular system in chronic heart fai...

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Autores principales: Duplancic, Darko, Cesarik, Marijan, Poljak, Nikola Kolja, Radman, Maja, Kovacic, Vedran, Radic, Josipa, Rogosic, Veljko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573827/
https://www.ncbi.nlm.nih.gov/pubmed/23430986
http://dx.doi.org/10.2147/CIA.S38349
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author Duplancic, Darko
Cesarik, Marijan
Poljak, Nikola Kolja
Radman, Maja
Kovacic, Vedran
Radic, Josipa
Rogosic, Veljko
author_facet Duplancic, Darko
Cesarik, Marijan
Poljak, Nikola Kolja
Radman, Maja
Kovacic, Vedran
Radic, Josipa
Rogosic, Veljko
author_sort Duplancic, Darko
collection PubMed
description The ubiquitous distribution of vitamin D receptors in the human body is responsible for the pleiotropic effects of vitamin D-receptor activation. We discuss the possible beneficial effects of a selective activator of vitamin D receptor, paricalcitol, on the cardiovascular system in chronic heart failure patients and chronic kidney patients, in light of new trials. Paricalcitol should provide additional clinical benefits over the standard treatment for chronic kidney and heart failure, especially in cases of cardiorenal syndrome.
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spelling pubmed-35738272013-02-21 The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection Duplancic, Darko Cesarik, Marijan Poljak, Nikola Kolja Radman, Maja Kovacic, Vedran Radic, Josipa Rogosic, Veljko Clin Interv Aging Review The ubiquitous distribution of vitamin D receptors in the human body is responsible for the pleiotropic effects of vitamin D-receptor activation. We discuss the possible beneficial effects of a selective activator of vitamin D receptor, paricalcitol, on the cardiovascular system in chronic heart failure patients and chronic kidney patients, in light of new trials. Paricalcitol should provide additional clinical benefits over the standard treatment for chronic kidney and heart failure, especially in cases of cardiorenal syndrome. Dove Medical Press 2013 2013-02-11 /pmc/articles/PMC3573827/ /pubmed/23430986 http://dx.doi.org/10.2147/CIA.S38349 Text en © 2013 Duplancic et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Duplancic, Darko
Cesarik, Marijan
Poljak, Nikola Kolja
Radman, Maja
Kovacic, Vedran
Radic, Josipa
Rogosic, Veljko
The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_full The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_fullStr The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_full_unstemmed The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_short The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_sort influence of selective vitamin d receptor activator paricalcitol on cardiovascular system and cardiorenal protection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573827/
https://www.ncbi.nlm.nih.gov/pubmed/23430986
http://dx.doi.org/10.2147/CIA.S38349
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