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Transcript and protein profiling identifies signaling, growth arrest, apoptosis, and NF-κB survival signatures following GNRH receptor activation

GNRH significantly inhibits proliferation of a proportion of cancer cell lines by activating GNRH receptor (GNRHR)-G protein signaling. Therefore, manipulation of GNRHR signaling may have an under-utilized role in treating certain breast and ovarian cancers. However, the precise signaling pathways n...

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Detalles Bibliográficos
Autores principales:	Meyer, Colette, Sims, Andrew H, Morgan, Kevin, Harrison, Beth, Muir, Morwenna, Bai, Jianing, Faratian, Dana, Millar, Robert P, Langdon, Simon P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Endocrinology 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573841/ https://www.ncbi.nlm.nih.gov/pubmed/23202794 http://dx.doi.org/10.1530/ERC-12-0192

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