Acquired hypermethylation of the P16(INK4A) promoter in abdominal paraganglioma: relation to adverse tumor phenotype and predisposing mutation

Recurrent alterations in promoter methylation of tumor suppressor genes (TSGs) and LINE1 (L1RE1) repeat elements were previously reported in pheochromocytoma and abdominal paraganglioma. This study was undertaken to explore CpG methylation abnormalities in an extended tumor panel and assess possible...

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Detalles Bibliográficos
Autores principales: Kiss, Nimrod B, Muth, Andreas, Andreasson, Adam, Juhlin, C Christofer, Geli, Janos, Bäckdahl, Martin, Höög, Anders, Wängberg, Bo, Nilsson, Ola, Ahlman, Håkan, Larsson, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Endocrinology 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573842/
https://www.ncbi.nlm.nih.gov/pubmed/23154831
http://dx.doi.org/10.1530/ERC-12-0267

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