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Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells
BACKGROUND: There is evidence that the extent of the G2/M arrest following irradiation is correlated with tumour cell survival and hence therapeutic success. We studied the regulation of cellular response to radiation treatment by miR-21-mediated modulation of cell cycle progression in breast cancer...
Autores principales: | Anastasov, Nataša, Höfig, Ines, Vasconcellos, Iria Gonzalez, Rappl, Kristina, Braselmann, Herbert, Ludyga, Natalie, Auer, Gert, Aubele, Michaela, Atkinson, Michael J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573984/ https://www.ncbi.nlm.nih.gov/pubmed/23216894 http://dx.doi.org/10.1186/1748-717X-7-206 |
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