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Development of a gene therapy strategy to target hepatocellular carcinoma based inhibition of protein phosphatase 2A using the α-fetoprotein promoter enhancer and pgk promoter: an in vitro and in vivo study

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Current therapies are insufficient, making HCC an intractable disease. Our previous studies confirmed that inhibition of protein phosphatase 2A (PP2A) may provide a promising therapeutic strat...

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Detalles Bibliográficos
Autores principales:	Li, Wei, Li, Dao-Ming, Chen, Kai, Chen, Zheng, Zong, Yang, Yin, Hong, Xu, Ze-Kuan, Zhu, Yi, Gong, Fei-Ran, Tao, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574000/ https://www.ncbi.nlm.nih.gov/pubmed/23173703 http://dx.doi.org/10.1186/1471-2407-12-547

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