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TRIF Is Required for TLR4 Mediated Adjuvant Effects on T Cell Clonal Expansion
Toll like receptor 4 (TLR4) is an important pattern recognition receptor with the ability to drive potent innate immune responses and also to modulate adaptive immune responses needed for long term protection. Activation of TLR4 by its ligands is mediated by engagement of the adapter proteins MyD88...
Autores principales: | Gandhapudi, Siva K., Chilton, Paula M., Mitchell, Thomas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574014/ https://www.ncbi.nlm.nih.gov/pubmed/23457630 http://dx.doi.org/10.1371/journal.pone.0056855 |
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