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Prenatal Metformin Exposure in Mice Programs the Metabolic Phenotype of the Offspring during a High Fat Diet at Adulthood

AIMS: The antidiabetic drug metformin is currently used prior and during pregnancy for polycystic ovary syndrome, as well as during gestational diabetes mellitus. We investigated the effects of prenatal metformin exposure on the metabolic phenotype of the offspring during adulthood in mice. METHODS:...

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Detalles Bibliográficos
Autores principales:	Salomäki, Henriikka, Vähätalo, Laura H., Laurila, Kirsti, Jäppinen, Norma T., Penttinen, Anna-Maija, Ailanen, Liisa, Ilyasizadeh, Juan, Pesonen, Ullamari, Koulu, Markku
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574083/ https://www.ncbi.nlm.nih.gov/pubmed/23457588 http://dx.doi.org/10.1371/journal.pone.0056594

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