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Rapid Inverse Planning for Pressure-Driven Drug Infusions in the Brain
Infusing drugs directly into the brain is advantageous to oral or intravenous delivery for large molecules or drugs requiring high local concentrations with low off-target exposure. However, surgeons manually planning the cannula position for drug delivery in the brain face a challenging three-dimen...
Autores principales: | Rosenbluth, Kathryn H., Martin, Alastair J., Mittermeyer, Stephan, Eschermann, Jan, Dickinson, Peter J., Bankiewicz, Krystof S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574124/ https://www.ncbi.nlm.nih.gov/pubmed/23457563 http://dx.doi.org/10.1371/journal.pone.0056397 |
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