Cargando…

The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS)

Using an ovine model of polycystic ovary syndrome (PCOS), (pregnant ewes injected with testosterone propionate (TP) (100 mg twice weekly) from day (d)62 to d102 of d147 gestation (maternal injection – MI-TP)), we previously reported female offspring with normal glucose tolerance but hyperinsulinemia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rae, Mick, Grace, Cathal, Hogg, Kirsten, Wilson, Lisa Marie, McHaffie, Sophie L., Ramaswamy, Seshadri, MacCallum, Janis, Connolly, Fiona, McNeilly, Alan S., Duncan, Colin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574134/ https://www.ncbi.nlm.nih.gov/pubmed/23457541 http://dx.doi.org/10.1371/journal.pone.0056263

Ejemplares similares

Developmental programming of polycystic ovary syndrome (PCOS): prenatal androgens establish pancreatic islet α/β cell ratio and subsequent insulin secretion
por: Ramaswamy, S., et al.
Publicado: (2016)

In an Ovine Model of Polycystic Ovary Syndrome (PCOS) Prenatal Androgens Suppress Female Fetal Renal Gluconeogenesis
por: Connolly, Fiona, et al.
Publicado: (2015)

The In Utero Programming Effect of Increased Maternal Androgens and a Direct Fetal Intervention on Liver and Metabolic Function in Adult Sheep
por: Hogg, Kirsten, et al.
Publicado: (2011)

The Local Effects of Ovarian Diathermy in an Ovine Model of Polycystic Ovary Syndrome
por: Connolly, Fiona, et al.
Publicado: (2014)

Role of Androgen Receptor for Reconsidering the “True” Polycystic Ovarian Morphology in PCOS
por: Gao, Xue-ying, et al.
Publicado: (2020)

Two Cases of Adrenal Malignancy With Macroscopic Fat
por: Wilkinson, Tom, et al.
Publicado: (2023)

Inhibin removes the inhibitory effects of activin on steroid enzyme expression and androgen production by normal ovarian thecal cells
por: Young, J M, et al.
Publicado: (2012)

Androgen Receptor CAG Repeats Length Polymorphism and the Risk of Polycystic Ovarian Syndrome (PCOS)
por: Rajender, Singh, et al.
Publicado: (2013)

Effects of CreER(T2), 4-OH Tamoxifen, and Gender on CFU-F Assays
por: McHaffie, Sophie L., et al.
Publicado: (2016)

Best Practices for the Coordinated Care of Patients With Neuroendocrine Tumors Undergoing Peptide Receptor Radionuclide Therapy
por: Hendifar, Andrew E., et al.
Publicado: (2022)

Young female with abdominal pain and intra‐abdominal free fluid: The risk of confirmation bias associated with point‐of‐care ultrasound
por: Joyce, Laura, et al.
Publicado: (2022)

Correction: Androgen Receptor CAG Repeats Length Polymorphism and the Risk of Polycystic Ovarian Syndrome (PCOS)
por: Rajender, Singh, et al.
Publicado: (2013)

Correction: Androgen Receptor CAG Repeats Length Polymorphism and the Risk of Polycystic Ovarian Syndrome (PCOS)
por: Rajender, Singh, et al.
Publicado: (2013)

MON-213 Evaluation of Type 2 Diabetes and Cardiovascular Disease Risk Factors in Reproductive-Age Women with Polycystic Ovary Syndrome (PCOS) Using the 2014 Androgen Excess and PCOS Society Criteria for the Polycystic Ovarian Morphology
por: Kazemi, Maryam, et al.
Publicado: (2019)

Association of Insulin Resistance and Elevated Androgen Levels with Polycystic Ovarian Syndrome (PCOS): A Review of Literature
por: Xu, Yalan, et al.
Publicado: (2022)

Activin B is produced early in antral follicular development and suppresses thecal androgen production
por: Young, J M, et al.
Publicado: (2012)

The Mechanism of Androgen Actions in PCOS Etiology
por: Rodriguez Paris, Valentina, et al.
Publicado: (2019)

Hirsutism, Normal Androgens and Diagnosis of PCOS
por: Spritzer, Poli Mara, et al.
Publicado: (2022)

Reconsidering the Polycystic Ovary Syndrome (PCOS)
por: Gleicher, Norbert, et al.
Publicado: (2022)

Data sharing among data monitoring committees and responsibilities to patients and science
por: Chalmers, Iain, et al.
Publicado: (2013)

Evaluating the impact of integrated development: are we asking the right questions? A systematic review
por: Ahner-McHaffie, Tessa W, et al.
Publicado: (2018)

Epigenetic Mechanism Underlying the Development of Polycystic Ovary Syndrome (PCOS)-Like Phenotypes in Prenatally Androgenized Rhesus Monkeys
por: Xu, Ning, et al.
Publicado: (2011)

Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats
por: Tyndall, Victoria, et al.
Publicado: (2012)

Polycystic Pancreas
por: Sonavane, Amey D., et al.
Publicado: (2016)

Changes in androgens and insulin sensitivity indexes throughout pregnancy in women with polycystic ovary syndrome (PCOS): relationships with adverse outcomes
por: Falbo, Angela, et al.
Publicado: (2010)

MON-LB010 Cyclic Progesterone Therapy for Androgenic Polycystic Ovary Syndrome (PCOS) - A Systematic Review of the Literature
por: Shirin, Sonia, et al.
Publicado: (2020)

The role of androgen and its related signals in PCOS
por: Ye, Wenting, et al.
Publicado: (2020)

Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS)
por: Froment, Pascal, et al.
Publicado: (2006)

Polycystic Ovary Syndrome (PCOS) Transition at Menopause
por: Shah, Duru, et al.
Publicado: (2021)

Molecular Research on Polycystic Ovary Syndrome (PCOS)
por: Daniele, Simona, et al.
Publicado: (2023)

Evaluation of the effect of metformin and aspirin on utero placental circulation of pregnant women with PCOS
por: Jamal, Ashraf, et al.
Publicado: (2012)

Sun Tzu y el arte de los negocios : seis estrategias fundamentales para el hombre de negocios
por: McNeilly, Mark
Publicado: (1999)

In utero exposure to low doses of environmental pollutants disrupts fetal ovarian development in sheep
por: Fowler, Paul A., et al.
Publicado: (2008)

“PCOS is Like having a Disease”: The Everyday Stress of Living with Polycystic Ovarian Syndrome (PCOS)
por: Divya, M, et al.
Publicado: (2022)

MicroRNAs Related to Polycystic Ovary Syndrome (PCOS)
por: Sørensen, Anja Elaine, et al.
Publicado: (2014)

Polycystic Ovary Syndrome (PCOS), Diagnostic Criteria, and AMH
por: Mohammad, Majid Bani, et al.
Publicado: (2017)

Correlation of Subclinical Hypothyroidism With Polycystic Ovary Syndrome (PCOS)
por: Fatima, Murk, et al.
Publicado: (2020)

Probable discrepancy in the prevalence of polycystic ovarian syndrome (PCOS)
por: Javed, Haseeba, et al.
Publicado: (2022)

Editorial: Polycystic ovary syndrome (PCOS): Mechanism and management
por: Wang, Yishu, et al.
Publicado: (2022)

Faecal Microbiota Transplantation for Clostridium Difficile – a local perspective
por: Diamond, C, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2bntom3bf855kpi8dkh3fsud7o