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MAP Kinase-Mediated c-fos Regulation Relies on a Histone Acetylation Relay Switch

Gene activation is often associated with high levels of histone acetylation. Enhanced acetylation levels can promote the recruitment of further chromatin modifying complexes or the basal transcription machinery. Here, we have studied MAP kinase-mediated upregulation of c-fos and uncover a role for h...

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Detalles Bibliográficos
Autores principales: O'Donnell, Amanda, Yang, Shen-Hsi, Sharrocks, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574235/
https://www.ncbi.nlm.nih.gov/pubmed/18374651
http://dx.doi.org/10.1016/j.molcel.2008.01.019