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MAP Kinase-Mediated c-fos Regulation Relies on a Histone Acetylation Relay Switch
Gene activation is often associated with high levels of histone acetylation. Enhanced acetylation levels can promote the recruitment of further chromatin modifying complexes or the basal transcription machinery. Here, we have studied MAP kinase-mediated upregulation of c-fos and uncover a role for h...
Autores principales: | O'Donnell, Amanda, Yang, Shen-Hsi, Sharrocks, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574235/ https://www.ncbi.nlm.nih.gov/pubmed/18374651 http://dx.doi.org/10.1016/j.molcel.2008.01.019 |
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