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Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway

Neutrophil apoptosis and subsequent nonphlogistic clearance by surrounding phagocytes are key to the successful resolution of neutrophilic inflammation, with dysregulated apoptosis reported in multiple human inflammatory diseases. Enhancing neutrophil apoptosis has proresolution and anti-inflammator...

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Detalles Bibliográficos
Autores principales:	Lucas, Christopher D., Allen, Keith C., Dorward, David A., Hoodless, Laura J., Melrose, Lauren A., Marwick, John A., Tucker, Carl S., Haslett, Christopher, Duffin, Rodger, Rossi, Adriano G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2013
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574292/ https://www.ncbi.nlm.nih.gov/pubmed/23195034 http://dx.doi.org/10.1096/fj.12-218990

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