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Development of a Novel Two Dimensional Surface Plasmon Resonance Sensor Using Multiplied Beam Splitting Optics

A novel two dimensional surface plasmon resonance (SPR) sensor system with a multi-point sensing region is described. The use of multiplied beam splitting optics, as a core technology, permitted multi-point sensing to be achieved. This system was capable of simultaneously measuring nine sensing poin...

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Detalles Bibliográficos
Autores principales: Hemmi, Akihide, Mizumura, Ryosuke, Kawanishi, Ryuta, Nakajima, Hizuru, Zeng, Hulie, Uchiyama, Katsumi, Kaneki, Noriaki, Imato, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574705/
https://www.ncbi.nlm.nih.gov/pubmed/23299626
http://dx.doi.org/10.3390/s130100801
Descripción
Sumario:A novel two dimensional surface plasmon resonance (SPR) sensor system with a multi-point sensing region is described. The use of multiplied beam splitting optics, as a core technology, permitted multi-point sensing to be achieved. This system was capable of simultaneously measuring nine sensing points. Calibration curves for sucrose obtained on nine sensing points were linear in the range of 0–10% with a correlation factor of 0.996–0.998 with a relative standard deviation of 0.090–4.0%. The detection limits defined as S/N = 3 were 1.98 × 10(−6)–3.91 × 10(−5) RIU. This sensitivity is comparable to that of conventional SPR sensors.