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Congenital Rubella Syndrome in Fiji, 1995–2010
Setting. A nationwide study in Fiji. Objective. To describe the incidence of congenital rubella syndrome (CRS) and its relationship to the incidence of notified cases of rubella in Fiji from 1995 to 2010. Design. Descriptive, retrospective review of all recorded congenital abnormalities associated w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574747/ https://www.ncbi.nlm.nih.gov/pubmed/23431317 http://dx.doi.org/10.1155/2013/956234 |
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author | Singh, Sheetalpreet Bingwor, Frances Tayler-Smith, Katherine Manzi, Marcel Marks, Guy B. |
author_facet | Singh, Sheetalpreet Bingwor, Frances Tayler-Smith, Katherine Manzi, Marcel Marks, Guy B. |
author_sort | Singh, Sheetalpreet |
collection | PubMed |
description | Setting. A nationwide study in Fiji. Objective. To describe the incidence of congenital rubella syndrome (CRS) and its relationship to the incidence of notified cases of rubella in Fiji from 1995 to 2010. Design. Descriptive, retrospective review of all recorded congenital abnormalities associated with live births in Fiji over 16 years. Results. There were 294 infants who met the criteria for CRS. Of these, 95% were classified as “suspected” cases, 5% were “clinically confirmed,” and none were “laboratory confirmed cases”. There was a significant linear increase over the study period in the incidence of CRS (odds ratio 1.045 per year, 95% CI 1.019 to 1.071, P ≤ 0.001). There was no significant association between the incidence of CRS and the reported incidence of rubella (P = 0.3). Conclusion. There is a rising trend in reports of suspected CRS cases in Fiji. This highlights the need to strengthen surveillance for CRS through improvements in clinical and laboratory diagnosis to confirm or exclude suspected cases. It is also important to ensure high coverage of rubella vaccination in Fiji. |
format | Online Article Text |
id | pubmed-3574747 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-35747472013-02-21 Congenital Rubella Syndrome in Fiji, 1995–2010 Singh, Sheetalpreet Bingwor, Frances Tayler-Smith, Katherine Manzi, Marcel Marks, Guy B. J Trop Med Research Article Setting. A nationwide study in Fiji. Objective. To describe the incidence of congenital rubella syndrome (CRS) and its relationship to the incidence of notified cases of rubella in Fiji from 1995 to 2010. Design. Descriptive, retrospective review of all recorded congenital abnormalities associated with live births in Fiji over 16 years. Results. There were 294 infants who met the criteria for CRS. Of these, 95% were classified as “suspected” cases, 5% were “clinically confirmed,” and none were “laboratory confirmed cases”. There was a significant linear increase over the study period in the incidence of CRS (odds ratio 1.045 per year, 95% CI 1.019 to 1.071, P ≤ 0.001). There was no significant association between the incidence of CRS and the reported incidence of rubella (P = 0.3). Conclusion. There is a rising trend in reports of suspected CRS cases in Fiji. This highlights the need to strengthen surveillance for CRS through improvements in clinical and laboratory diagnosis to confirm or exclude suspected cases. It is also important to ensure high coverage of rubella vaccination in Fiji. Hindawi Publishing Corporation 2013 2013-02-03 /pmc/articles/PMC3574747/ /pubmed/23431317 http://dx.doi.org/10.1155/2013/956234 Text en Copyright © 2013 Sheetalpreet Singh et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Singh, Sheetalpreet Bingwor, Frances Tayler-Smith, Katherine Manzi, Marcel Marks, Guy B. Congenital Rubella Syndrome in Fiji, 1995–2010 |
title | Congenital Rubella Syndrome in Fiji, 1995–2010 |
title_full | Congenital Rubella Syndrome in Fiji, 1995–2010 |
title_fullStr | Congenital Rubella Syndrome in Fiji, 1995–2010 |
title_full_unstemmed | Congenital Rubella Syndrome in Fiji, 1995–2010 |
title_short | Congenital Rubella Syndrome in Fiji, 1995–2010 |
title_sort | congenital rubella syndrome in fiji, 1995–2010 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574747/ https://www.ncbi.nlm.nih.gov/pubmed/23431317 http://dx.doi.org/10.1155/2013/956234 |
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