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Congenital Rubella Syndrome in Fiji, 1995–2010

Setting. A nationwide study in Fiji. Objective. To describe the incidence of congenital rubella syndrome (CRS) and its relationship to the incidence of notified cases of rubella in Fiji from 1995 to 2010. Design. Descriptive, retrospective review of all recorded congenital abnormalities associated w...

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Detalles Bibliográficos
Autores principales: Singh, Sheetalpreet, Bingwor, Frances, Tayler-Smith, Katherine, Manzi, Marcel, Marks, Guy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574747/
https://www.ncbi.nlm.nih.gov/pubmed/23431317
http://dx.doi.org/10.1155/2013/956234
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author Singh, Sheetalpreet
Bingwor, Frances
Tayler-Smith, Katherine
Manzi, Marcel
Marks, Guy B.
author_facet Singh, Sheetalpreet
Bingwor, Frances
Tayler-Smith, Katherine
Manzi, Marcel
Marks, Guy B.
author_sort Singh, Sheetalpreet
collection PubMed
description Setting. A nationwide study in Fiji. Objective. To describe the incidence of congenital rubella syndrome (CRS) and its relationship to the incidence of notified cases of rubella in Fiji from 1995 to 2010. Design. Descriptive, retrospective review of all recorded congenital abnormalities associated with live births in Fiji over 16 years. Results. There were 294 infants who met the criteria for CRS. Of these, 95% were classified as “suspected” cases, 5% were “clinically confirmed,” and none were “laboratory confirmed cases”. There was a significant linear increase over the study period in the incidence of CRS (odds ratio 1.045 per year, 95% CI 1.019 to 1.071, P ≤ 0.001). There was no significant association between the incidence of CRS and the reported incidence of rubella (P = 0.3). Conclusion. There is a rising trend in reports of suspected CRS cases in Fiji. This highlights the need to strengthen surveillance for CRS through improvements in clinical and laboratory diagnosis to confirm or exclude suspected cases. It is also important to ensure high coverage of rubella vaccination in Fiji.
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spelling pubmed-35747472013-02-21 Congenital Rubella Syndrome in Fiji, 1995–2010 Singh, Sheetalpreet Bingwor, Frances Tayler-Smith, Katherine Manzi, Marcel Marks, Guy B. J Trop Med Research Article Setting. A nationwide study in Fiji. Objective. To describe the incidence of congenital rubella syndrome (CRS) and its relationship to the incidence of notified cases of rubella in Fiji from 1995 to 2010. Design. Descriptive, retrospective review of all recorded congenital abnormalities associated with live births in Fiji over 16 years. Results. There were 294 infants who met the criteria for CRS. Of these, 95% were classified as “suspected” cases, 5% were “clinically confirmed,” and none were “laboratory confirmed cases”. There was a significant linear increase over the study period in the incidence of CRS (odds ratio 1.045 per year, 95% CI 1.019 to 1.071, P ≤ 0.001). There was no significant association between the incidence of CRS and the reported incidence of rubella (P = 0.3). Conclusion. There is a rising trend in reports of suspected CRS cases in Fiji. This highlights the need to strengthen surveillance for CRS through improvements in clinical and laboratory diagnosis to confirm or exclude suspected cases. It is also important to ensure high coverage of rubella vaccination in Fiji. Hindawi Publishing Corporation 2013 2013-02-03 /pmc/articles/PMC3574747/ /pubmed/23431317 http://dx.doi.org/10.1155/2013/956234 Text en Copyright © 2013 Sheetalpreet Singh et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Singh, Sheetalpreet
Bingwor, Frances
Tayler-Smith, Katherine
Manzi, Marcel
Marks, Guy B.
Congenital Rubella Syndrome in Fiji, 1995–2010
title Congenital Rubella Syndrome in Fiji, 1995–2010
title_full Congenital Rubella Syndrome in Fiji, 1995–2010
title_fullStr Congenital Rubella Syndrome in Fiji, 1995–2010
title_full_unstemmed Congenital Rubella Syndrome in Fiji, 1995–2010
title_short Congenital Rubella Syndrome in Fiji, 1995–2010
title_sort congenital rubella syndrome in fiji, 1995–2010
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574747/
https://www.ncbi.nlm.nih.gov/pubmed/23431317
http://dx.doi.org/10.1155/2013/956234
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