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A novel drug–phospholipid complex enriched with micelles: preparation and evaluation in vitro and in vivo
Mixed micelles are widely used to increase solubility and bioavailability of poorly soluble drugs. One promising antitumor drug candidate is 20(S)-protopanaxadiol (PPD), although its clinical application is limited by low water solubility and poor bioavailability after oral administration. In this s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575161/ https://www.ncbi.nlm.nih.gov/pubmed/23431115 http://dx.doi.org/10.2147/IJN.S39526 |