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Preparation and in vitro and in vivo characterization of cyclosporin A-loaded, PEGylated chitosan-modified, lipid-based nanoparticles
BACKGROUND AND METHODS: A new cyclosporin A-loaded, PEGylated chitosan-modified lipid-based nanoparticle was developed to improve upon the formulation of cyclosporin A. PEGylated chitosan, synthesized in three steps using mild reaction conditions, was used to modify the nanoparticles. Cyclosporin A-...
Autores principales: | Zhang, Ling, Zhao, Zhi-Liang, Wei, Xiao-Hong, Liu, Jin-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575177/ https://www.ncbi.nlm.nih.gov/pubmed/23429854 http://dx.doi.org/10.2147/IJN.S39685 |
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