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MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis

BACKGROUND: Tumor suppressor p53 is mutated in a wide variety of human cancers and plays a critical role in anoikis, which is essential for preventing tumorigenesis. Recently, we found that a nucleolar protein, Myb-binding protein 1a (MYBBP1A), was involved in p53 activation. However, the function o...

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Detalles Bibliográficos
Autores principales: Akaogi, Kensuke, Ono, Wakana, Hayashi, Yuki, Kishimoto, Hiroyuki, Yanagisawa, Junn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575238/
https://www.ncbi.nlm.nih.gov/pubmed/23388179
http://dx.doi.org/10.1186/1471-2407-13-65

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