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EGFR Gene Copy Number as a Prognostic Marker in Colorectal Cancer Patients Treated with Cetuximab or Panitumumab: A Systematic Review and Meta Analysis

BACKGROUND: The epidermal growth factor receptor (EGFR) gene copy number (GCN) has been previously demonstrated to correlate with the clinical outcome of colorectal cancer (CRC) treated with anti-EGFR monoclonal antibodies (mAbs), although it remains controversial. We conducted a systematic review a...

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Detalles Bibliográficos
Autores principales: Jiang, Zheng, Li, Chunxiang, Li, Fuyuan, Wang, Xishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575344/
https://www.ncbi.nlm.nih.gov/pubmed/23441167
http://dx.doi.org/10.1371/journal.pone.0056205