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Mirk/Dyrk1B mediates G0/G1 to S phase cell cycle progression and cell survival involving MAPK/ERK signaling in human cancer cells

BACKGROUND: Mirk/Dyrk1B contributes to G0 arrest by destabilization of cyclin D1 and stabilization of p27kip1 to maintain the viability of quiescent human cancer cells, and it could be negatively regulated by mitogenic-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) signa...

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Detalles Bibliográficos
Autores principales:	Gao, Jingchun, Zhao, Yi, Lv, Yunyi, Chen, Yamin, Wei, Bing, Tian, Jianxin, Yang, Zhihai, Kong, Fandou, Pang, Jian, Liu, Jiwei, Shi, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575355/ https://www.ncbi.nlm.nih.gov/pubmed/23311607 http://dx.doi.org/10.1186/1475-2867-13-2

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