Magnetic Separation and Antibiotics Selection Enable Enrichment of Cells with ZFN/TALEN-Induced Mutations

The ability to enrich cells with targeted mutations greatly facilitates the process of using engineered nucleases, including zinc-finger nucleases and transcription activator-like effector nucleases, to construct such cells. We previously used surrogate reporters to enrich cells containing nuclease-...

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Detalles Bibliográficos
Autores principales: Kim, Hyojin, Kim, Myung-Sun, Wee, Gabbine, Lee, Choong-il, Kim, Hyongbum, Kim, Jin-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575389/
https://www.ncbi.nlm.nih.gov/pubmed/23441197
http://dx.doi.org/10.1371/journal.pone.0056476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575389/
https://www.ncbi.nlm.nih.gov/pubmed/23441197
http://dx.doi.org/10.1371/journal.pone.0056476

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