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Bridging Cancer Biology with the Clinic: Relative Expression of a GRHL2-Mediated Gene-Set Pair Predicts Breast Cancer Metastasis

Identification and characterization of crucial gene target(s) that will allow focused therapeutics development remains a challenge. We have interrogated the putative therapeutic targets associated with the transcription factor Grainy head-like 2 (GRHL2), a critical epithelial regulatory factor. We d...

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Detalles Bibliográficos
Autores principales: Yang, Xinan, Vasudevan, Prabhakaran, Parekh, Vishwas, Penev, Aleks, Cunningham, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575392/
https://www.ncbi.nlm.nih.gov/pubmed/23441166
http://dx.doi.org/10.1371/journal.pone.0056195