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Human Concentrative Nucleoside Transporter 3 Transfection with Ultrasound and Microbubbles in Nucleoside Transport Deficient HEK293 Cells Greatly Increases Gemcitabine Uptake

Gemcitabine is a hydrophilic clinical anticancer drug that requires nucleoside transporters to cross plasma membranes and enter cells. Pancreatic adenocarcinomas with low levels of nucleoside transporters are generally resistant to gemcitabine and are currently a clinical problem. We tested whether...

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Detalles Bibliográficos
Autores principales:	Paproski, Robert J., Yao, Sylvia Y. M., Favis, Nicole, Evans, David, Young, James D., Cass, Carol E., Zemp, Roger J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575408/ https://www.ncbi.nlm.nih.gov/pubmed/23441192 http://dx.doi.org/10.1371/journal.pone.0056423

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