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Regulation of Spine Density and Morphology by IQGAP1 Protein Domains

IQGAP1 is a scaffolding protein that regulates spine number. We now show a differential role for IQGAP1 domains in spine morphogenesis, in which a region of the N-terminus that promotes Arp2/3-mediated actin polymerization and branching stimulates spine head formation while a region that binds to Cd...

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Detalles Bibliográficos
Autores principales:	Jausoro, Ignacio, Mestres, Ivan, Quassollo, Gonzalo, Masseroni, Lujan, Heredia, Florencia, Caceres, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575492/ https://www.ncbi.nlm.nih.gov/pubmed/23441206 http://dx.doi.org/10.1371/journal.pone.0056574

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